Global Exposome Cohorts

collections

Data & sample collections

181 collections

  • 3xG

    3xG study (Gezondheid, Gemeenten, Geboorten)
    3xG (read: three times G) is a local birth cohort study to follow up the health of the citizens in the communities of Dessel, Mol and Retie in Belgium. The purpose is to monitor environmental and lifestyle exposure and health effects by following up 301 newborns till the age of 18 years old, with human biomonitoring and frequent questionnaires. Website (Dutch): https://studie3xg.be/nl

  • 4FirHealth

    Firefighting occupational exposure and early effects on the health of operational forces
    Nowadays, forest fires are an important public health issue due to the emission of a countless number of hazardous pollutants including particulate matter (PM), principally the finest fraction (PM<2.5 µm) that penetrate more deeply into the respiratory tract, several volatile organic compounds e.g. polycyclic aromatic hydrocarbons (PAHs), and metals. PM, PAHs, and metals are pollutants of major concern due to their high environmental persistence, toxicity, and carcinogenicity, thus being responsible for the initiation of cardio-respiratory inflammatory processes. Fires emissions may affect short- and long-term health and quality of life of exposed populations, particularly of the occupationally exposed firefighting operational forces. The cohort characteizes the occupational exposure of firefighters from different corporations in the Porto metropolitan area by performing human (bio)monitoring assays (personal air, urine, saliva, and skin contamination) and (in vitro) health risk assessment to motivate the implementation of mitigation strategies and propote occupational safety and health.

  • ABCD

    Adolescent Brain Cognitive Development Study
    The Adolescent Brain Cognitive Development (ABCD) Study is a longitudinal U.S. cohort study that has followed nearly 12,000 children recruited at ages 9–10 to examine brain development, cognition, mental health, and substance use trajectories into adulthood. It collects multimodal data including structural and functional MRI, neurocognitive assessments, mental and physical health measures, genetics, biospecimens, and detailed environmental and social information. Importantly, participant residential addresses are geocoded and used to link external contextual data such as neighborhood socioeconomic conditions, air pollution, crime, greenspace, and school characteristics. This linkage allows researchers to study how place-based and environmental exposures interact with biology and behavior to shape adolescent development. https://abcdstudy.org/

  • ABCD

    The Amsterdam Born Children and their Development Study
    The ABCD-study is a large longitudinal research study on the health of 8000 Amsterdam born children. We investigate which factors in early pregnancy and childhood influence the health of these children.

  • African-PREDICT

    African Prospective study on the Early Detection and Identification of Cardiovascular disease and Hypertension
    The African-PREDICT study is a longitudinal cohort study investigating the early development and progression of hypertension and cardiovascular disease in young, healthy adults. Approximately 1,200 Black and White adults aged 20 to 30 years were recruited and assessed between 2013 and 2017 from Potchefstroom and surrounding areas in the North West Province of South Africa. Participants were enrolled through community health workers, workplace outreach, and public advertisements, with efforts to include individuals from low-, middle-, and high-socioeconomic backgrounds. The cohort is planned to be followed up on every five years.

  • Airwave

    Airwave Health Monitoring Study
    The Airwave Tissue Bank is an epidemiological study of police officers and staff in Great Britain. It was established in 2003 to investigate possible long-term health effects associated with use of TETRA, the personal radio system used by the police service. Participant recruitment was piloted from June 2004 via paper questionnaire and health screen. After two years, the pilot was deemed successful and, with some revisions to the protocol, the main phase of recruitment began in 2006. We toured the country, spending time with police forces keen to enroll their officers and staff. Recruitment ended in March 2015 forming a baseline of approximately 53,000. In November 2015, we began a programme of follow-up health screens for participants whose previous screen was at least 5-years prior. This continued until the outbreak of COVID-19 in March 2020. During the following two pandemic years the cohort volunteered for two important components of the REACT Study, making valuable contributions to research into diagnostic methods. The cohort has been richly phenotyped, flagged to routine records, and has a substantial biobank of blood and urine samples. It provides an excellent and unique resource to study the genetic, metabolic, occupational and lifestyle factors associated with mental health and cognitive performance among a predominantly male and young adult workforce with a well-defined organisational hierarchy.

  • ALBION

    Aiginition Longitudinal Biomarker Investigation Of Neurodegeneration
    The ALBION cohort is an ongoing prospective observational study of middle-aged and older adults designed to study the biological, lifestyle, and environmental determinants of cognitive aging and Alzheimer's disease. The study integrates comprehensive clinical, neuropsychological, lifestyle, and dietary assessments with multimodal biomarker assessments, including cerebrospinal fluid biomarkers, neuroimaging, and omics technologies. Participants undergo longitudinal follow-up to characterize trajectories of cognitive decline and neurodegenerative disease progression. The cohort aims to understand how environmental, lifestyle, and biological exposures interact to influence cognitive aging and Alzheimer's disease risk, supporting the identification of early biomarkers and opportunities for precision prevention.

  • ALERT

    Assessment of Lead Exposure and Risk Tracking in children
    Despite the magnitude of the problem, Brazil lacks representative national studies on blood lead levels in children, currently relying on local and sporadic investigations. In this context, the partnership between the Ministry of Health, Vital Strategies Brazil, and the University of São Paulo represents a strategic opportunity to integrate scientific evidence into decision-making, strengthening the country's institutional response to lead exposure, in alignment with the guidelines of the Unified Health System (SUS) and the National Health Surveillance Policy. This project aims to implement a national survey of lead exposure in preschool children, through biomonitoring and the study of associated risk factors in Brazil, with national representativeness, in order to generate qualified scientific evidence on blood lead levels in children aged 1 to 5 years and 11 months, and the main risk factors associated with exposure. Through interinstitutional partnerships, we are including other biomarkers.

  • ALSPAC

    Avon Longitudinal Study of Parents and Children
    Based at the University of Bristol, the Avon Longitudinal Study of Parents and Children (ALSPAC), also known as Children of the 90s, is a world-leading birth cohort study. Between April 1991 and December 1992 we recruited more than 14,000 pregnant women into the study and these women (some of whom had two pregnancies or multiple births during the recruitment period), the children arising from the pregnancy, and their partners have been followed up intensively over two decades. We are the most detailed study of its kind in the world and we provide the international research community with a rich resource for the study of the environmental and genetic factors that affect a person’s health and development. Through our research we aim to inform policy and practices that will provide a better life for future generations.

  • AM-MENTAL

    Algorithmic management at work and Mental Health
    What: AM-MENTAL is a longitudinal cohort study representative of working adults in Spain that examines exposure to algorithmic management and its association with mental health and well-being. Why: The cohort was created because algorithmic management is rapidly expanding in the labour market, while its mental health implications are poorly understood and insufficiently addressed in regulation. What for: The purpose is to generate robust evidence on psychosocial risks linked to algorithmic management and identify groups that may be particularly vulnerable. Results are intended to inform policy, regulation, and workplace practices through evidence-based recommendations developed with stakeholder involvement. How: The cohort follows a representative working population over time using repeated survey data, measuring exposure to algorithmic management, working conditions, mental health outcomes, musculoskeletal pain and occupational injuries.

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