collections

Data & sample collections

19 collections

  • BIB

    Born in Bradford
    Born in Bradford (BiB) started in 2007 as a response to the poor health outcomes for children in Bradford. Pregnant women were recruited when they attended the Bradford Royal Infirmary for their routine maternity care. Participants were asked to complete a questionnaire about different aspects of their lives including demographics information, physical and mental health and socio-economic information. Between 2007 and 2011, 12,453 pregnant women were recruited and 3,353 of their partners. Participants also gave permission for routine data linkage for themselves and their children. The BiB cohort is split between approximately 50% South Asian and 50% non-South Asian participants. BiB has completed a number of sub-sample studies including BiB1000, which focused on exploring ethnic variation and risk factors of childhood obesity. Data collection included questionnaires with parents when the children were between 6 and 36 months at 6 monthly intervals.The ALLIN and MeDALL studies focused on the relationships between childhood allergies and infections. Data collection for these studies were done via a questionnaire and, for the MeDALL study, children were asked to have a skin allergy test. Since 2016, BiB have undertaken a full cohort follow-up compromising of home visits for data collection through questionnaires, school visits where children carried out cognitive assessments, and a child measurement programme where children were weighed and measured, had their activity levels measured, and were asked to give a blood sample. From the findings of these studies, BiB have developed a range of additional research projects such as evaluating and developing new interventions to improve health; for example, focusing on reducing childhood obesity, increasing physical activity, improving oral health and improving mental wellbeing. BiB have gone beyond functioning as an observational birth cohort and are actively trying to build and strengthen local research capacity and translate evidence to practice.
  • BiSC

    Barcelona Life Study Cohort
    The Barcelona Life Study Cohort (BiSC) is an exposome cohort, aiming to comprehensively evaluate the socio-environmental and genetic determinants (i) of foetal and child health, growth, and development towards adult life and (ii) of maternal mental and physical health and wellbeing during pregnancy and afterwards, while shedding light on the underlying biological mechanisms. https://projectebisc.org/en/home/
  • CELSPAC-TNG

    Central European Longitudinal Study of Parents and Children: The Next Generation
    This prospective birth cohort is designed to follow up 7000 children from their prenatal period to adolescence with the aim of assessing EXPOSOME factors potentially affecting children health.
  • DNBC

    The Danish National Birth Cohort
    The Danish National Birth Cohort (DNBC) was established to investigate the causal link between exposures in early life and disease later on and the possibilites for disease prevention. Initial data collection information was collected by computer-assisted telephone interviews with the women twice during pregnancy and when their children were six and 18 months old. Further data collections were conducted when the children were 7, 11 and 18 years old. For more details, please visit the DNBC homepage.
  • EDEN

    Study on the pre and early postnatal determinants of child health and development
    The EDEN study is a French bicentric generalist cohort study (Heude et al. IJE 2016). Pregnant women were invited to participate during their prenatal visit, before the 24th week of amenorrhea, in the obstetrics and gynecology departments of the Poitiers and Nancy university hospitals. Recruitment took place from February 2003 to January 2006. The exclusion criteria were: twin pregnancy, diagnosis of insulin-dependent diabetes, inability to speak and read French, intention to move from the region within three years of inclusion . Among the women invited, 53% agreed to participate (n = 2,002). Detailed information on phenotypes and exposures were collected through questionnaires from pregnancy until 8 years and through clinical examinations of the mother (at 24 weeks of amenorrhoea, at delivery and 5–6 years after delivery) and the child (at birth and 1, 3 and 5–6 years, including cognitive assessments at 3 and 5–6 years). At 5–6 years, 1255 children were still followed up.
  • ELSPAC

    European Longitudinal Study of Pregnancy and Childhood
  • ENVIRONAGE

    ENVIRonmental influence ON early AGEing
    Within the ongoing population-based prospective birth cohort study ENVIRONAGE we explore new dimensions in the current understanding of human ageing and its interaction with the environment
  • GenR

    The Generation R Study
    The Generation R Study is a population-based prospective cohort study from fetal life until adulthood and is conducted in Rotterdam, the second largest city in the Netherlands. The study is designed to identify early environmental and genetic causes and causal pathways leading to normal and abnormal growth, development and health from fetal life, childhood and young adulthood. This multidisciplinary study focuses on several health outcomes including behaviour and cognition, body composition, eye development, growth, hearing, heart and vascular development, infectious disease and immunity, oral health and facial growth, respiratory health, allergy and skin disorders of children and their parents. Main exposures of interest include environmental, endocrine, genomic (genetic, epigenetic, microbiome), lifestyle related, nutritional and socio-demographic determinants. The Generation R study enrolled 9,153 mothers with a delivery date from April 2002 until January 2006, who participated with a total of 9,778 pregnancies in the study from which 9,901 children were expected to be born; the mothers gave birth to 9,749 live born children.
  • GenR Next

    Generation R Next
    The Generation R Next Study is a population-based cohort study from preconception onwards. In total, about 3600 women are being included in the period 2017-2021. Of all included couples, about 30% is included during the preconception, about 60% during the first trimester of pregnancy and about 10% in the third trimester of pregnancy.
  • HELIX

    Human Early Life Exposome study
    https://athleteproject.eu/helix-cohort/ The HELIX cohort represents a collaborative study across six established and ongoing longitudinal population-based birth cohort studies in six European countries (France, Greece, Lithuania, Norway, Spain, and the United Kingdom). HELIX collected data from 1,663 mother-child pairs recruited during pregnancy. Data was retroactively collected and harmonized for the pregnancy period, and biomarkers, omics signatures and child health outcomes were measured at ages 6-11 years. A second follow-up visit was conducted at ages 12-18 years with 864 adolescents participating where biomarkers, omics signatures and health outcomes were again collected.