ELFE

Description

General Design

Type

Cohort study

Cohort type

Birth cohort

Data collection type

Retrospective, Prospective

Design

Longitudinal

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Start/End data collection

2011 until 2021

Design paper

Cohort Profile: The French national cohort of children (ELFE): birth to 5 years.

Population

Continents

Europe

Countries

France

Number of participants

18329

Organisations

• Inserm (INSERM)

  France

  https://www.inserm.fr

Contributors

• Marie Aline Charlesmarie-aline.charles@inserm.fr

Data dictionaries

Subpopulations

Collection events

Networks

• 

  INTEGRATE Large Medical Cohorts

  The INTEGRATE-LMedC consortium will develop a new concept to guide and support decision-making for the next-generation research infrastructure (RI) to facilitate efficient utilization and harmonization of large medical cohorts (LMedC), and to accelerate scientific and medical breakthroughs in Europe and beyond.

  WebsiteNetwork detailsCatalogue
• 

  The LifeCycle Project

  A Europe-wide network of cohort studies started in early life Cohort studies started from pregnancy or childhood give the unique opportunity to relate early-life stressors with variation in development, health and disease throughout the life course. Moreover, advanced analytical approaches used in observational studies can help identify causality and potential for early-life interventions on factors that cannot be easily studied in experimental settings. These factors include socioeconomic circumstances, migration, urban environment as well as lifestyle-related determinants and will be given particular focus in our project. We will set up a European pregnancy and childhood cohort, the EU Child Cohort Network, which brings together extensive existing data from more than 250,000 European children and their parents. These cohorts enable studies in multiple generations because of their detailed phenotyping of both parents and children. The network will bring together existing successful multidisciplinary cohort studies, which all started before or during pregnancy or in childhood. Together, they span the full life course and contain detailed phenotypical information as well as biological samples. The EU Child Cohort Network will optimize exploitation of more than 40 available cohort resources in Europe and will enable innovative research on identification of novel markers of early-life stressors related to health trajectories throughout the full life cycle. Although LifeCycle partners and their cohorts have taken the initiative for this unique collaboration, the network is open to other partners with population-based cohorts started in early life, specifically those from Eastern and Southern Europe. To ensure that this will be a Europe-wide, open and sustainable network, which exceeds the LifeCycle Project duration, we will introduce a data sharing platform taking account of ethical, legal and societal implications, we will organize yearly meetings open to all European pregnancy and child cohort researchers and we will start a fellowship programme for exchange between these European cohorts.

  WebsiteNetwork detailsCatalogue
• 

  LongITools Health & Environment Dynamics

  LongITools is a European research project studying the interactions between the environment, lifestyle and health in determining the risks of chronic cardiovascular and metabolic diseases.

  WebsiteNetwork detailsCatalogue
• 

  Global Exposome Cohorts

  The Global Exposome Cohort Catalogue is an international registry, based on the FAIR principle, of exposome cohorts with worldwide coverage. The objective is to generate a shared, public space for findability/discovery of cohorts with datasets that are relevant for the exposome field (i.e., that can contribute to answering exposome-related research questions), containing source metadata for each listed resource. We define a cohort as: a longitudinal population (birth, mother-child, adolescent, adult, or multi-generational) in which individual-level data are collected on health outcomes and/or exposures of interest. The Global Exposome Cohort Catalogue hosts metadata for each cohort, focusing on elements such as (Type of Cohort, Timing and duration of data collection, Exposure domains covered [e.g., chemical, urban, lifestyle, social], Geographical scope, Contact information for dataset access, Link to external website or data repository).

  Network detailsCatalogue

Publications

Access conditions

Data access conditions

health or medical or biomedical research

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Release type

Continuous

Linkage options

yes

Funding & Acknowledgements

Funding

The Ministries of the Environment, Health and Research provided initial funding for the ELFE cohort. The funding for the first 5 years of childhood follow-up was obtained from the national ‘Investment for the Future’ research funding program for a joint project bringing together the ELFE and Epipage 2 cohorts.

Documentation