Children are particularly vulnerable to environmental hazards. The ATHLETE project will measure a wide range of environmental exposures (urban, chemical, lifestyle and social risk factors) during pregnancy, childhood, and adolescence. The project will then link this “early-life exposome” to children’s biological responses and cardiometabolic, respiratory, and mental health. The results will help us to better understand and prevent health damage from environmental agents from the earliest parts of the life course onward.
WebsiteNetwork detailsCatalogueEDEN
Study on the pre and early postnatal determinants of child health and development
Description
The EDEN study is a French bicentric generalist cohort study (Heude et al. IJE 2016). Pregnant women were invited to participate during their prenatal visit, before the 24th week of amenorrhea, in the obstetrics and gynecology departments of the Poitiers and Nancy university hospitals. Recruitment took place from February 2003 to January 2006. The exclusion criteria were: twin pregnancy, diagnosis of insulin-dependent diabetes, inability to speak and read French, intention to move from the region within three years of inclusion . Among the women invited, 53% agreed to participate (n = 2,002). Detailed information on phenotypes and exposures were collected through questionnaires from pregnancy until 8 years and through clinical examinations of the mother (at 24 weeks of amenorrhoea, at delivery and 5–6 years after delivery) and the child (at birth and 1, 3 and 5–6 years, including cognitive assessments at 3 and 5–6 years). At 5–6 years, 1255 children were still followed up.
General Design
- Type
- Cohort study
- Cohort type
- Population cohort
- Data collection type
- Retrospective, Prospective
- Design
- Longitudinal
- Start/End data collection
- 2003 until 2014
- Design paper
- EDEN mother-child cohort study group. Cohort Profile: The EDEN mother-child cohort on the prenatal and early postnatal determinants of child health and development.
Population
- Continents
- Europe
- Number of participants
- 2002
Organisations
Lead organisations
- Inserm (INSERM)Francehttps://www.inserm.fr
Contributors
Data dictionaries
Tables
Tables and their description
| Name | Description | |
|---|---|---|
No results for current selection |
Variables
Variables and their description
| Variable | Table | |
|---|---|---|
No results for current selection |
Subpopulations
List of subpopulations for this resource
| Name | Description | Number of participants | |
|---|---|---|---|
No results for current selection |
Collection events
List of collection events defined for this resource
| Name | Description | Participants | Start end year | |
|---|---|---|---|---|
No results for current selection |
Networks
Part of networks
Publications
Access conditions
- Submission of the project proposal to the cohort PI (Barbara Heude)
- Approval of the project by the EDEN steering committee (takes 1 month)
- Signature of a data access agreement (DAA)
- Data made available for analysis by the data manager (credentials will be sent to the person requesting access to the data)
- Data access conditions
- health or medical or biomedical research
- Release type
- Continuous
Funding & Acknowledgements
- Funding
- The study relied on many different sources of funding including Inserm, University Paris 11, the French Medical Research Foundation and the National Research Agency and also from national and European programs and project grants. A more comprehensive list of funders can be found on the EDEN website, along with other information
- Acknowledgements
- The authors are extremely grateful to all the families who took part in this study, the midwives and psychologists for recruiting and following them, and the whole EDEN team, including research scientists, engineers, technicians and managers.