collections

Data & sample collections

49 collections

  • ABCD

    The Amsterdam Born Children and their Development Study
    The ABCD-study is a large longitudinal research study on the health of 8000 Amsterdam born children. We investigate which factors in early pregnancy and childhood influence the health of these children.
  • ALSPAC

    Avon Longitudinal Study of Parents and Children
    Based at the University of Bristol, the Avon Longitudinal Study of Parents and Children (ALSPAC), also known as Children of the 90s, is a world-leading birth cohort study. Between April 1991 and December 1992 we recruited more than 14,000 pregnant women into the study and these women (some of whom had two pregnancies or multiple births during the recruitment period), the children arising from the pregnancy, and their partners have been followed up intensively over two decades. We are the most detailed study of its kind in the world and we provide the international research community with a rich resource for the study of the environmental and genetic factors that affect a person’s health and development. Through our research we aim to inform policy and practices that will provide a better life for future generations.
  • BIB

    Born in Bradford
    Born in Bradford (BiB) started in 2007 as a response to the poor health outcomes for children in Bradford. Pregnant women were recruited when they attended the Bradford Royal Infirmary for their routine maternity care. Participants were asked to complete a questionnaire about different aspects of their lives including demographics information, physical and mental health and socio-economic information. Between 2007 and 2011, 12,453 pregnant women were recruited and 3,353 of their partners. Participants also gave permission for routine data linkage for themselves and their children. The BiB cohort is split between approximately 50% South Asian and 50% non-South Asian participants. BiB has completed a number of sub-sample studies including BiB1000, which focused on exploring ethnic variation and risk factors of childhood obesity. Data collection included questionnaires with parents when the children were between 6 and 36 months at 6 monthly intervals.The ALLIN and MeDALL studies focused on the relationships between childhood allergies and infections. Data collection for these studies were done via a questionnaire and, for the MeDALL study, children were asked to have a skin allergy test. Since 2016, BiB have undertaken a full cohort follow-up compromising of home visits for data collection through questionnaires, school visits where children carried out cognitive assessments, and a child measurement programme where children were weighed and measured, had their activity levels measured, and were asked to give a blood sample. From the findings of these studies, BiB have developed a range of additional research projects such as evaluating and developing new interventions to improve health; for example, focusing on reducing childhood obesity, increasing physical activity, improving oral health and improving mental wellbeing. BiB have gone beyond functioning as an observational birth cohort and are actively trying to build and strengthen local research capacity and translate evidence to practice.
  • BiSC

    Barcelona Life Study Cohort
    The Barcelona Life Study Cohort (BiSC) is an exposome cohort, aiming to comprehensively evaluate the socio-environmental and genetic determinants (i) of foetal and child health, growth, and development towards adult life and (ii) of maternal mental and physical health and wellbeing during pregnancy and afterwards, while shedding light on the underlying biological mechanisms. https://projectebisc.org/en/home/
  • CELSPAC-TNG

    Central European Longitudinal Study of Parents and Children: The Next Generation
    This prospective birth cohort is designed to follow up 7000 children from their prenatal period to adolescence with the aim of assessing EXPOSOME factors potentially affecting children health.
  • CHOP

    Childhood Obesity Programme
    The European Childhood Obesity Project (CHOP) was a one-year multicentre double-blind randomized controlled intervention trial including 1678 children (registered at ClinicalTrials.gov: NCT00338689). The aim was to test whether feeding infant formula, which differ in their level of milk proteins, can influence infant growth and the risk of later childhood obesity ('early protein hypothesis'). Healthy singleton term infants born between 1st October 2002 and 31st July 2004 were recruited in five European countries (Belgium, Germany, Italy, Poland, Spain) during their 8 weeks of life. They were randomized to cow-milk based formula with either higher or lower protein-content. Additionally a reference group of breastfed children was included. After the intervention, children were prospectively followed up until the age of 11 years.
  • CONSTANCES

    Cohorte des Consultants des Centres d’Examens de Santé
  • DFBC

    Dutch Famine Birth Cohort study
    The cohort was set up to investigate the effects of acute maternal undernutrition during specific stages of gestation on the offspring’s adult health. The main outcomes of interest of the DFBC are chronic cardiovascular and metabolic diseases, ageing and mental health. Differences in various outcomes have been found between participants exposed to famine and unexposed participants. Although statistically significant, these differences are not very large, therefore adjusting for exposure group enables researchers to use DFBC data in pooled analyses.
  • DNBC

    The Danish National Birth Cohort
    The Danish National Birth Cohort (DNBC) was established to investigate the causal link between exposures in early life and disease later on and the possibilites for disease prevention. Initial data collection information was collected by computer-assisted telephone interviews with the women twice during pregnancy and when their children were six and 18 months old. Further data collections were conducted when the children were 7, 11 and 18 years old. For more details, please visit the DNBC homepage.
  • EDEN

    Study on the pre and early postnatal determinants of child health and development
    The EDEN study is a French bicentric generalist cohort study (Heude et al. IJE 2016). Pregnant women were invited to participate during their prenatal visit, before the 24th week of amenorrhea, in the obstetrics and gynecology departments of the Poitiers and Nancy university hospitals. Recruitment took place from February 2003 to January 2006. The exclusion criteria were: twin pregnancy, diagnosis of insulin-dependent diabetes, inability to speak and read French, intention to move from the region within three years of inclusion . Among the women invited, 53% agreed to participate (n = 2,002). Detailed information on phenotypes and exposures were collected through questionnaires from pregnancy until 8 years and through clinical examinations of the mother (at 24 weeks of amenorrhoea, at delivery and 5–6 years after delivery) and the child (at birth and 1, 3 and 5–6 years, including cognitive assessments at 3 and 5–6 years). At 5–6 years, 1255 children were still followed up.